The Vienna Nomogram
[Dr. Shaw's personal website]

This experimental-stage chart/nomogram can be used to determine the optimal number of transrectal prostate gland core biopsies to take/obtain when PSA is between 2-10 and DRE is negative, depending on the man's age and prostate gland TRUS size. The system's cancer detection rate of 37% is equal to octant pattern plus a follow-up biopsy session if initial one was benign1.
Vienna Nomogram

Total serum PSA between 2-10 ng/mL

TRUS size cc.

Age range in years:

50 years old or younger

51-60

61-70

older than 70

0-30cc

 8 cores 8 cores 8 cores 6 cores

31-40cc

 12 cores 10 cores 8 cores 6 cores

41-50cc

 14 cores 12 cores 10 cores 8 cores

51-60cc

 16 cores  14 cores 12 cores 10 cores

61-70cc

 18 cores 16 cores 14 cores 12 cores

greater than 70cc

 18 cores 18 cores 16 cores 14 cores

References:

  1. Remzi M, et. al. [from Dept. Urology, U. of Vienna, Vienna, Austria], "The Vienna Nomogram: Validation of a Novel Biopsy Strategy Defining the Optimal Number of Cores Based on Patient Age and Total Prostate Volume", J.Urology 174:1256-1261, October, 2005.

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