Breast
ductal carcinoma in-situ (DCIS)
Your VNPI Calculation
Worksheet
Remember that the calculations will be summed into
a single number which can then place your case into one of three treatment groups: CBS only,
CBS plus XRT, or mastectomy. It is HUGELY important for you to keep in mind
that this does not constitute a treatment command or final decision. It simply gives one line
of evidence, a statistics-based basis for considering your options as you discuss them with
your doctors.
TUMOR SIZE
By whatever measure, the following are the criteria for assignment of
size points (such were originally assigned from the pathology tissue
studies):
-
equal to or less
than 1.5cm...............1 point
-
from 1.6
cm. to 4.0 cm.........................2 points
-
equal to
or greater than 4.1 cm.......3 points
YOUR
CANCER'S NUCLEAR GRADE:
-
tumor nuclei
have diffuse chromatin, absent/inapparent nucleoli and average no larger than 1 to 1.5
RBC diameters:
nuclear grade 1 (one point)
-
tumor nuclei
have coarse chromatin, present but infrequent nucleoli and average no larger than 1.5
to 2.0 RBC diameters:
nuclear grade 2 (two points)
-
tumor nuclei
have vesicular chromatin, frequent nucleoli and average larger than two RBC
diameters:
nuclear grade 3 (three
points)
THINNEST SURGICAL
MARGIN:
-
closest/thinnest
measured margin is equal to or greater than 1.0 cm............1 point
-
closest/thinnest
measured margin is between 0.1-0.9 cm.................2 points
-
closest/thinnest
measured margin is less than 0.1 cm....................3
points
Age:
- 61 or
older............1 point
- 40-60.................2 points
- 39 or
younger....................3 points
Non-beta-weighted
VNPI CALCULATION FORMULA:
VNPI SCORE= tumor-size [_____pts] plus nuclear [_____pts]
plus margin [_____pts] plus age [___pts]=_____total VNPI
points
VNPI
DECISION GROUPS [here]
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page***
(posted 17 Dec. 2000; latest update 13 January
2004)
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